Prophylaxis Regimen for Hemophilia A Patients

PHASE4CompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

July 28, 2022

Primary Completion Date

September 3, 2024

Study Completion Date

October 17, 2024

Conditions
Hemophilia AProphylaxis of Bleeding
Interventions
BIOLOGICAL

Damoctocog alfa-pegol is a recombinant B-domain deleted human coagulation FVIII variant site specifically conjugated with a 60 kDa, branched (30 kDa each) polyethylene glycol (PEG).

"Dosage Levels:~* 40 IU/kg/dose two times per week~* 50 IU/kg/dose every 5 days~* 60 IU/kg/dose, Less frequent dosing (e.g. every 7 days), the total recommended maximum dose/infusion is 6000 IU."

Trial Locations (13)

30301

Aflac Cancer and Blood Disorders Center, Atlanta

30912

Augusta University Medical Center, Augusta

33136

University of Miami Hospital, Miami

48824

Michigan State University, East Lansing

52240

The University of Iowa - Div of Sponsored Programs, Iowa City

55455

University of Minnesota Medical Center, Minneapolis

60612

Rush University Medical Center, Chicago

77030

Gulf States Hemophilia & Thrombophilia Center-UT Physicians, Houston

90001

Orthopaedic Institute for Children, Los Angeles

92354

Dr. Akshat Jain - Loma Linda University Medical Center, Loma Linda

92408

Loma Linda Children's Hospital, San Bernardino

Colorado

"University of Colorado , Renal Research Office"

08901

Rutgers Robert Wood Johnson Medical School, New Brunswick

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bayer

INDUSTRY

NCT05036278 - Prophylaxis Regimen for Hemophilia A Patients | Biotech Hunter | Biotech Hunter