Multiple-Dose Study to Evaluate the Safety and Efficacy of IXT-m200

PHASE2TerminatedINTERVENTIONAL
Enrollment

61

Participants

Timeline

Start Date

June 9, 2022

Primary Completion Date

September 11, 2023

Study Completion Date

November 7, 2023

Conditions
Methamphetamine-dependenceMethamphetamine Abuse
Interventions
DRUG

IXT-m200

IXT-m200 binds METH with high selectivity and affinity. The product contains a murine METH-binding variable region and the constant domains of a human immunoglobulin G (IgG) 2κ. This antibody isotype was chosen because of the lower risk of immune response compared to an IgG1 or IgG3. IXT-m200 targets METH, does not rely on binding to any endogenous target for its action, and has been well-tolerated in previous clinical studies.

OTHER

Placebo

Saline

Trial Locations (9)

45417

Midwest Clinical Research Center, Dayton

60712

Pillar Clinical Research, Lincolnwood

72211

Woodlands International Research Group, Little Rock

72712

Pillar Clinical Research, Bentonville

75080

Pillar Clinical Research, Richardson

75115

InSite Clinical Research, DeSoto

77008

HD Research, Houston

84015

Alpine Research, Clinton

92103

Artemis Institute for Clinical Research, San Diego

Sponsors
All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

InterveXion Therapeutics, LLC

INDUSTRY