61
Participants
Start Date
June 9, 2022
Primary Completion Date
September 11, 2023
Study Completion Date
November 7, 2023
IXT-m200
IXT-m200 binds METH with high selectivity and affinity. The product contains a murine METH-binding variable region and the constant domains of a human immunoglobulin G (IgG) 2κ. This antibody isotype was chosen because of the lower risk of immune response compared to an IgG1 or IgG3. IXT-m200 targets METH, does not rely on binding to any endogenous target for its action, and has been well-tolerated in previous clinical studies.
Placebo
Saline
Midwest Clinical Research Center, Dayton
Pillar Clinical Research, Lincolnwood
Woodlands International Research Group, Little Rock
Pillar Clinical Research, Bentonville
Pillar Clinical Research, Richardson
InSite Clinical Research, DeSoto
HD Research, Houston
Alpine Research, Clinton
Artemis Institute for Clinical Research, San Diego
Lead Sponsor
National Institute on Drug Abuse (NIDA)
NIH
InterveXion Therapeutics, LLC
INDUSTRY