Evaluation of the Safety and Immunogenicity of SII Vaccine Constructs Based on the SARS-CoV-2 (COVID-19) Variant in Adults

PHASE1/PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

February 4, 2022

Primary Completion Date

August 31, 2022

Study Completion Date

August 31, 2022

Conditions
Covid19
Interventions
BIOLOGICAL

SII B.1.351

"Intramuscular (deltoid) injections of 3 μg SII B.1.351 and 50 μg Matrix-M1 Adjuvant,~1 or 2 doses:1 on Day 0 and ± 1 on Day 21."

BIOLOGICAL

SII B.1.351

"Intramuscular (deltoid) injections of 5 μg SII B.1.351 and 50 μg Matrix-M1 Adjuvant,~1 or 2 doses:1 on Day 0 and ± 1 on Day 21."

BIOLOGICAL

SII Bivalent

Intramuscular (deltoid) injections of 6 μg SII Bivalent and 50 μg Matrix-M1 Adjuvant, 2 doses: 1 on Day 0 and 1 on Day 21.

BIOLOGICAL

SII Bivalent

Intramuscular (deltoid) injections of 10 μg SII Bivalent and 50 μg Matrix-M1 Adjuvant, 2 doses: 1 on Day 0 and 1 on Day 21.

BIOLOGICAL

SII B.1.617.2

"Intramuscular (deltoid) injections of 5 μg SII B.1.617.2 and 50 μg Matrix-M1 Adjuvant,~1 or 2 doses:1 on Day 0 and ± 1 on Day 21."

Trial Locations (4)

2010

Holdsworth House Medical Practice - Sydney, Sydney

2035

Australian Clinical Research Network (ACRN), Maroubra

3124

Emeritus Research, Melbourne

3320

University Hospital Geelong-Barwon Health, Geelong

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novavax

INDUSTRY