60
Participants
Start Date
September 7, 2021
Primary Completion Date
February 16, 2023
Study Completion Date
June 26, 2023
Carboplatin
Carboplatin will be administered after completion of Sintilimab by IV infusion to achieve an initial target AUC of 5 mg/mL/min on Day 1.
Cisplatin
Cisplatin 75 mg/m\^2 will be administered after completion of Sintilimab by IV infusion on Day 1.
Etoposide
Etoposide 100 mg/m\^2 will be administered by IV infusion following carboplatin or cisplatin administration, during the induction phase on Day 1 through 3 of each cycle. On Days 2 and 3, patients will receive etoposide alone.
Sintilimab
Sintilimab 200 mg will be administered by IV infusion following IBI110 on Day 1 of each 21-day .
IBI110
IBI110 RP2D will be administered by IV infusion on Day 1 of each 21-day .
Shanghai Pulmonary Hospital, Shanghai
Innovent Biologics (Suzhou) Co. Ltd.
INDUSTRY