NCT05023967View on ClinicalTrials.gov

Metformin and Nightly Fasting in Women With Early Breast Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

April 4, 2023

Primary Completion Date

November 20, 2025

Study Completion Date

November 20, 2025

Conditions
Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Breast Ductal Carcinoma In SituInvasive Breast Carcinoma
Interventions
PROCEDURE

Biospecimen Collection

Undergo collection of blood and tissue samples

DRUG

Extended Release Metformin Hydrochloride

Given PO

OTHER

Monitoring

Use continuous glucose monitoring system

OTHER

Nutritional Assessment

Receive nutritional counseling

OTHER

Short-Term Fasting

Perform intermittent fasting

Trial Locations (3)

16128

RECRUITING

Galliera Hospital, Genoa

20141

RECRUITING

European Institute of Oncology, Milan

77030

RECRUITING

M D Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

M.D. Anderson Cancer Center

OTHER