The Effect of Voxelotor on Cerebral Hemodynamic Response in Children with Sickle Cell Anemia

PHASE2TerminatedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

March 28, 2022

Primary Completion Date

October 22, 2024

Study Completion Date

October 22, 2024

Conditions
Sickle Cell Anemia in Children
Interventions
DRUG

Voxelotor

Voxelotor is taken orally once a day. Participants 12 years or older will take 1500 mg/day. Participants younger than 12 years of age will receive a dose based on their body weight to provide exposure corresponding to the adult dose of 1500 mg/day.

Trial Locations (2)

30322

Children's Healthcare of Atlanta, Atlanta

30342

Aflac Sickle Cell Comprehensive Clinics at Children's Healthcare of Atlanta, Scottish Rite, Atlanta

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

Amy Tang

OTHER

NCT05018728 - The Effect of Voxelotor on Cerebral Hemodynamic Response in Children with Sickle Cell Anemia | Biotech Hunter | Biotech Hunter