Rhythmic Light Therapy for Alzheimer's Disease Patients

NACompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

January 10, 2022

Primary Completion Date

July 12, 2023

Study Completion Date

July 12, 2023

Conditions
Mild Cognitive Impairment
Interventions
DEVICE

Tailored Rhythmic Lighting Intervention

40 hertz (Hz) rhythmic lighting (RL) for a duration of 1 hour. The flicker frequency of the 40 Hz RL will be 40 Hz and the stimulation will be a square wave with a 50 % duty cycle (i.e., 12.5 milliseconds light- on and 12.5 milliseconds light-off). The RL will provide a 30 lux of red light on a vertical plane at the eye level.

DEVICE

Placebo Rhythmic Lighting Intervention

Placebo rhythmic light (RL) for a duration of 1 hour. In the placebo RL condition, the duty cycle will be delivered at randomly varying frequencies of 20 Hz and 50 Hz, specifically avoiding the frequency of 40 Hz. The placebo RL conditions will provide a 30 lux of red light on a vertical plane at the eye level.

Trial Locations (2)

10029

Icahn School of Medicine at Mount Sinai, New York

12204

Light and Health Research Center, Menands

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

Icahn School of Medicine at Mount Sinai

OTHER

NCT05015478 - Rhythmic Light Therapy for Alzheimer's Disease Patients | Biotech Hunter | Biotech Hunter