NCT05008276View on ClinicalTrials.gov

Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

September 27, 2021

Primary Completion Date

December 1, 2027

Study Completion Date

December 1, 2027

Conditions
Type 2 Diabetes MellitusDiabetic Kidney DiseaseAdolescent ObesityPre DiabetesKidney HypoxiaPuberty
Interventions
DRUG

Aminohippurate Sodium Inj 20%

Diagnostic aid/agent used to measure effective renal plasma flow (ERPF)

DRUG

Iohexol Inj 300 MG/ML

Diagnostic aid/agent used to measure glomerular filtration rate (GFR)

DRUG

Dextran 40

Diagnostic aid/agent used to measure glomerular size and selectivity

Trial Locations (2)

80045

RECRUITING

Children's Hospital Colorado, Aurora

98102

RECRUITING

Seattle Children's Hospital, Seattle

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

collaborator

Seattle Children's Hospital

OTHER

collaborator

University of Colorado, Denver

OTHER

lead

Petter Bjornstad

OTHER