Effect of INO in Patients with Submassive and Massive PE

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

June 1, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2026

Conditions
Pulmonary EmbolismPulmonary Embolism Subacute Massive
Interventions
DRUG

inhaled nitric oxide (iNO)

"Inhaled nitric oxide (iNO), which is known mainly from the pulmonary hypertension literature for its therapeutic role in pulmonary arterial hypertension, has been proposed as a potential pharmacologic adjunct to standard anticoagulation in acute PE.~Inhaled nitric oxide (iNO) will be administered at 30 ppm for 3 minutes. The measurements will be obtained/calculated before, during iNO administration, and after iNO has been withheld for 2 minutes."

Trial Locations (1)

90095

Ronald Reagan UCLA Medical Center, Los Angeles

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Mallinckrodt

INDUSTRY

lead

University of California, Los Angeles

OTHER