Impact of an Open Lung Extubation Strategy on Postoperative Pulmonary Complications

NACompletedINTERVENTIONAL
Enrollment

69

Participants

Timeline

Start Date

November 3, 2021

Primary Completion Date

December 17, 2021

Study Completion Date

January 17, 2022

Conditions
AnesthesiaPulmonary AtelectasisComplication of Anesthesia
Interventions
OTHER

Open lung extubation

Before starting emergence from anesthesia, the patient will be transferred to their hospital bed or stretcher and seated at 30 degrees. Secretions from the patients' oropharynx will be suctioned. To prevent the patient from coughing, the anesthetic gas or intravenous agent will be stopped after the transfer and suction procedure are completed. The FiO2 will be maintained at the same level or increased to 50% (minimum FiO2) with a fresh gas flow rate greater than or equal to 10 L.min-1. The ventilation mode will be changed to pressure support. The level of pressure support will be modified by the anesthesiologist to generate the same volumes as with controlled ventilation. The PEEP will be maintained at the same level. The minimum respiratory rate will be reduced by 4 min-1. The inspiratory flow for triggering will be 2 L.min-1.

OTHER

Conventional extubation

Before starting emergence from anesthesia, the patient will be transferred to his hospital bed or stretcher and kept in the supine position. Secretions from the patients' oropharynx will be suctioned. To prevent the patient from coughing, the anesthetic gas or intravenous agent will be stopped after the transfer and suction procedure are completed. The FiO2 will be increased to 100% with a fresh gas flow rate greater than or equal to 10 L.min-1. The ventilator will be stopped with the APL valve open to atmosphere. The patient will be manually ventilated with the reservoir bag until spontaneous ventilation resumes. Then, the patient may be manually assisted if the treating anesthesiologist deems it necessary.

Trial Locations (1)

H2X 3E4

Centre hospitalier de l'Université de Montréal (CHUM), Montreal

All Listed Sponsors
lead

Centre hospitalier de l'Université de Montréal (CHUM)

OTHER

NCT04993001 - Impact of an Open Lung Extubation Strategy on Postoperative Pulmonary Complications | Biotech Hunter | Biotech Hunter