NCT04992520View on ClinicalTrials.gov

Controlled Human Infection Model Challenge/Rechallenge

PHASE1CompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

April 26, 2022

Primary Completion Date

August 29, 2023

Study Completion Date

August 29, 2023

Conditions
Shigellosis
Interventions
BIOLOGICAL

Shigella sonnei 53G

Shigella sonnei (S. sonnei) strain 53G (Lot 1794); Mode of Administration: Delivered with sodium bicarbonate orally after a 90 minute fast.

BIOLOGICAL

Shigella flexneri 2a 2457T

Shigella flexneri (S. flexneri) strain 2457T (Lot 1617); Mode of Administration: Delivered with sodium bicarbonate orally after a 90 minute fast.

Trial Locations (1)

21224

Center for Immunization Research (CIR) at Johns Hopkins School of Public Health (JHSPH), Baltimore

All Listed Sponsors
collaborator

United States Department of Defense

FED

collaborator

Johns Hopkins University Center for Immunization Research (CIR)

UNKNOWN

lead

PATH

OTHER