Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic Fistula

NACompletedINTERVENTIONAL
Enrollment

299

Participants

Timeline

Start Date

August 6, 2021

Primary Completion Date

November 12, 2022

Study Completion Date

November 12, 2022

Conditions
Pancreatic FistulaPancreaticoduodenectomyComplication of Surgical Procedure
Interventions
PROCEDURE

Trans-Nasal Afferent Loop Decompression

A 14Fr silicon tube with multiple side holes within the range of 15 cm from the tip will be placed into the afferent jejunal limb with its end close to the pancreaticojejunostomy (\<3 cm) during the surgery. Continuous closed negative-pressure suction will be applied to that tube for 72 hours and after that the nasogastric tube will be removed. No nasogastric tube will be placed, or the nasogastric tube will be removed immediately after extubation.

PROCEDURE

Without Trans-Nasal Afferent Loop Decompression

No decompression tube will be placed. No nasogastric tube will be placed, or the nasogastric tube will be removed immediately after extubation.

Trial Locations (1)

210029

The First Affiliated Hospital with Nanjing Medical University, Nanjing

All Listed Sponsors
lead

The First Affiliated Hospital with Nanjing Medical University

OTHER

NCT04989868 - Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic Fistula | Biotech Hunter | Biotech Hunter