Evaluation of the Relevance of Pharmacogenetics in the Prescription Off Antidepressants in a Military Population

RecruitingOBSERVATIONAL
Enrollment

250

Participants

Timeline

Start Date

November 8, 2021

Primary Completion Date

February 28, 2025

Study Completion Date

November 30, 2025

Conditions
DepressionAnxietyPtsd
Interventions
BIOLOGICAL

Blood collection

A blood sample will be collected at enrollment to perform pharmacogenetics analyses.

OTHER

Questionnaires

Several questionnaires will be filled by the participants or by the clinicians at every study visits: Hospital anxiety depression scale (HAD), Post Traumatic Stress Disorder Checklist for DSM-5 (PCL-5), Quick inventory of depressive symptomatology - self rated (QiDS), Beck's Anxiety Inventory (BAI), World Health Organization Quality Of Life (WHOQOL-BREF), EuroQol Group questionnaire (EQ5D), Frequency, intensity, burden of side effects rating (FIBSER), Udvalg for Kliniske Undersøgelser - Side Effects Rating Scale - for Patients (UKU-SERS-PAT), Clinical Global impression (CGI), Montgomery and Asberg Depression Rating Scale (MADRS).

OTHER

Cognitive test battery (optional)

"For patients participating in the ELAN ancillary study : the participants will undergo a battery of neurocognitive tests assessing motivation (élan vital in French)."

Trial Locations (4)

13384

NOT_YET_RECRUITING

Hôpital d'Instruction des Armées Laveran, Marseille

83000

NOT_YET_RECRUITING

Hôpital d'Instruction des Armées Sainte-Anne, Toulon

92141

RECRUITING

Hôpital d'Instruction des Armées Percy, Clamart

94160

RECRUITING

Hôpital d'Instruction des Armées Bégin, Saint-Mandé

All Listed Sponsors
lead

Direction Centrale du Service de Santé des Armées

OTHER