A Proof of Concept Study to Evaluate the Effect of UB-421 in Combination With Chidamide on HIV Viral Reservoir

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 31, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
HIV-1-infection
Interventions
BIOLOGICAL

UB-421

10mg/kg weekly intravenous infusion to substitute for for antiretroviral therapy

OTHER

UB-421+chidamide

10 mg/kg UB-421 weekly intravenous infusion to substitute for antiretroviral therapy, and combined with oral 10 mg chidamide twice a week for 8 weeks. Chidamide taken on the one day and three days after the administration of UB-421.

All Listed Sponsors
lead

UBP Greater China (Shanghai) Co., Ltd

INDUSTRY