Better After CHoosing. Randomly Allocated or Patient Preference Based Treatment With Filgotinib or TNFi in RA (BACH)

PHASE4RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

May 12, 2021

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2025

Conditions
Rheumatoid Arthritis
Interventions
DRUG

Filgotinib

200 mg tablet once daily or 100 mg once daily

DRUG

Anti-Tumor Necrosis Factor Alpha Drug (Product)

Adalimumab subcutaneous injections 40 mg once every two weeks Etanercept subcutaneous injections 50 mg weekly

BEHAVIORAL

50 patients will have a Free Choice between Filgotinib and anti TNF

50 patients will be given the opportunity to choose between either TNFi (etanercept 50 mg SC once a week or adalimumab 40 mg SC once every two weeks) or filgotinib, an oral JAKi, 200 mg once a day while another group of 50 patients will be randomized to the same treatment arms.

Trial Locations (1)

8934AD

RECRUITING

Medical Center Leeuwarden MCL, Leeuwarden

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Galapagos NV

INDUSTRY

collaborator

Frisius Medisch Centrum

OTHER

collaborator

Leiden University Medical Center

OTHER

lead

R.Bos

OTHER