Treating Congestive HF With hiPSC-CMs Through Endocardial Injection

PHASE1UnknownINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

September 21, 2021

Primary Completion Date

December 30, 2022

Study Completion Date

July 31, 2023

Conditions
Cardiovascular DiseasesCongestive Heart FailureDilated Cardiomyopathy
Interventions
BIOLOGICAL

hiPSC-CM therapy

20 patients with congestive heart failure who met the inclusion and exclusion criteria will be recruited. After being fully informed and signed the informed consent, the patients will be randomly divided into two dosage groups: 100 million cells (10 patients) and 400 million cells (10 patients). Human iPSC-derived cardiomyocytes will be injected into the myocardium through a transcatheter endocardial injection system.

Trial Locations (1)

210000

RECRUITING

Help Therapeutics, Nanjing

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Xijing Hospital

OTHER

lead

Help Therapeutics

INDUSTRY