Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries

PHASE3RecruitingINTERVENTIONAL
Enrollment

640

Participants

Timeline

Start Date

November 11, 2021

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
Gender Dysphoria
Interventions
OTHER

Ultrasound guided Continuous Infraclavicular Brachial Plexus Block

20cc of 0.25% bupivacaine + 1:200K epinephrine will be administered at start of case, 20cc of 0.25% bupivacaine + 1:200K epinephrine at end of case, and 6cc/hr of 0.25% bupivacaine at post-op \[administered by anesthesiologist\]

OTHER

Ultrasound guided Continuous Femoral Nerve Block

20cc of 0.25% bupivacaine + 1:200K epinephrine will be administered at start of case, 20cc of 0.25% bupivacaine + 1:200K epinephrine at end of case, and 6cc/hr of 0.25% bupivacaine at post-op \[administered by anesthesiologist\]

OTHER

Ultrasound guided Pudendal Nerve Block

20-40cc of 0.25% bupivacaine + 1:200K epinephrine \[administered by anesthesiologist, pre-incision\]

DRUG

Bupivacaine

0.25% or 0.5% with or without 1:200K epinephrine

OTHER

Bilateral ultrasound guided Transversus Abdominis Plane Block

40-60cc of 0.25% bupivacaine + 1:200K epinephrine \[administered by anesthesiologist post-op or at end of surgery\]

OTHER

Bilateral spermatic cord block

10cc per spermatic cord of 0.5% bupivacaine \[administered by surgeon @ intraop\]

OTHER

Pecs I & II Block

0.25% bupivacaine: 15-30mL per side for Pecs I-III

OTHER

Local anesthetic

0.25% or 0.5% bupivacaine into the appropriate surgical site

Trial Locations (1)

90048

RECRUITING

Cedars-Sinai Medical Center - North and South Towers, Los Angeles

All Listed Sponsors
lead

Cedars-Sinai Medical Center

OTHER