Osteosarcoma Maintenance Therapy With OST31-164

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

October 21, 2021

Primary Completion Date

September 21, 2023

Study Completion Date

October 31, 2027

Conditions
Bone Cancer
Interventions
DRUG

OST31-164

Patients who will receive OST31-164 as a single agent every 3 weeks for 48 weeks with 4 doses constituting 1 treatment cycle (12 weeks per cycle). Each patient will receive treatment at a dose of 1x109 CFU until week 48 or until disease progression, unacceptable toxicity, or the patient meets any other treatment discontinuation criteria.

Trial Locations (21)

10467

Montefiore Medical Center, The Bronx

15224

UPMC Children's Hospital of Pittsburgh, Pittsburgh

19104

Children's Hospital of Philadelphia, Philadelphia

19803

Nemours/ Alfred I duPont Hospital for Children, Wilmington

21287

Johns Hopkins Medical Center, Baltimore

30322

Children's Healthcare of Atlanta, Atlanta

33701

Johns Hopkins All Children's Hospital, St. Petersburg

38105

St. Jude Children's Research Hospital, Memphis

43205

Nationwide Children's Hospital, Columbus

55455

University of Minnesota/Masonic Cancer Center, Minneapolis

60611

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago

75390

UT Southwestern Medical Center, Dallas

80045

Children's Hospital of Colorado, Aurora

90027

Kaiser Permanente Downey Medical Center, Los Angeles

92057

Children's Hospital of Orange County, Orange

92123

Rady Children's Hospital, San Diego

97239

Oregon Health & Science University, Portland

98101

Seattle Children's Hospital, Seattle

06106

Connecticut Children's, Hartford

02215

Dana-Farber Cancer Institute, Boston

07601

Hackensack University Medical Center, Hackensack

Sponsors
All Listed Sponsors
lead

Emerald Clinical Inc.

INDUSTRY