Trastuzumab Combined With Pertuzumab for Adjuvant Treatment of Breast Cancer After Neoadjuvant Therapy

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

450

Participants

Timeline

Start Date

August 1, 2021

Primary Completion Date

August 1, 2027

Study Completion Date

August 1, 2027

Conditions
Breast Cancer
Interventions
DRUG

Pyrotinib

Each subject in the test group will receive the test drug (pyrotinib) for 52 weeks, and will be followed up for at least 3 years from the start of randomization, until disease recurrence, intolerable toxicity, withdrawal of informed consent, or termination of the medication as per the investigator's judgment.

DRUG

Trastuzumab

Each enrolled subject will complete at least ≥ 24 weeks (8 drug delivery cycles) of trastuzumab combined with pertuzumab in the neoadjuvant and/or adjuvant treatment phase.

Trial Locations (1)

110004

Shengjing Hospital affiliated to China Medical University, Shenyang

All Listed Sponsors
lead

Shengjing Hospital

OTHER