450
Participants
Start Date
August 1, 2021
Primary Completion Date
August 1, 2027
Study Completion Date
August 1, 2027
Pyrotinib
Each subject in the test group will receive the test drug (pyrotinib) for 52 weeks, and will be followed up for at least 3 years from the start of randomization, until disease recurrence, intolerable toxicity, withdrawal of informed consent, or termination of the medication as per the investigator's judgment.
Trastuzumab
Each enrolled subject will complete at least ≥ 24 weeks (8 drug delivery cycles) of trastuzumab combined with pertuzumab in the neoadjuvant and/or adjuvant treatment phase.
Shengjing Hospital affiliated to China Medical University, Shenyang
Shengjing Hospital
OTHER