NCT04972123View on ClinicalTrials.gov

The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope

PHASE2CompletedINTERVENTIONAL

Enrollment

143

Participants

Timeline

Start Date

July 20, 2021

Primary Completion Date

August 25, 2023

Study Completion Date

August 31, 2023

Conditions

Syncope, Vasovagal

Interventions

DRUG

CPC - Capsaicin, Phenylephrine, Caffeine

CPC is a combination of Capsaicin, Phenylephrine and Caffeine

DIAGNOSTIC_TEST

Tilt Table Test

Participant will undergo tilt tablet testing using the Italian protocol (see reference section). The Italian protocol includes 20 minutes of passive tilt at 70 degrees (Passive Phase) followed by nitroglycerin (NTG) administration and tilt testing for another 15 minutes (NTG Phase).

DRUG

Placebo

Placebo for CPC

Trial Locations (1)

53792

University of Wisconsin- Madsion, Madison

All Listed Sponsors

lead

University of Wisconsin, Madison

OTHER

NCT04972123 - The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope | Biotech Hunter | Biotech Hunter