NCT04970342 - Validation of the Drug Impaired Driving Scenario (DIDS) on the CRCDS-miniSim | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

July 16, 2021

Primary Completion Date

August 21, 2021

Study Completion Date

August 21, 2021

Conditions

Driving BehaviorDriving Under the Influence

Interventions

DRUG

Placebo (Lactose) Capsule

Single dose on two of the three study visits, orally administered 40 minutes prior to cannabis dose

DRUG

0.75 mg Alprazolam Capsule

Single dose on one of the three study visits, orally administered 40 minutes prior to cannabis dose

DRUG

Cannabis (6.18% THC / <0.025% CBD)

Cannabis vapor is produced from 500 mg of dried plant material (6.18% THC / \<0.025% CBD). Subjects will inhale using the Foltin Puff Procedure over 10 minutes. Single inflated bag/dose consumed via inhalation 40 minutes after alprazolam dose on one of the three study visits.

DRUG

Cannabis (0%/ THC / 0% CBD)

Cannabis vapor is produced from 500 mg of dried plant material (0% THC / 0% CBD). Subjects will inhale using the Foltin Puff Procedure over 10 minutes. Single inflated bag/dose consumed via inhalation 40 minutes after alprazolam dose at two of the three study visits.

Trial Locations (1)

52242

National Advanced Driving Simulator, Iowa City