Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas (TORNADO)

PHASE2RecruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

December 7, 2022

Primary Completion Date

March 31, 2026

Study Completion Date

October 31, 2027

Conditions
Resectable Sarcoma
Interventions
DRUG

Doxorubicin

Doxorubicin will administered by intravenous infusion on day 1 every 3 weeks (75 mg/m²) up to 3 cycles

DRUG

Ifosfamide

Ifosfamide will be administered by intravenous infusion over 3 days every 3 weeks (9 g/m²) up to 3 cycles

DRUG

INCMGA00012

Retifanlimab will be administered by intravenous infusion on day 1every 3 weeks (375 mg) up to 3 cycles

Trial Locations (4)

33076

RECRUITING

Institut Bergonié, Bordeaux

94805

WITHDRAWN

Institut Gustave Roussy, Villejuif

Unknown

RECRUITING

Centre Léon Bérard, Lyon

NOT_YET_RECRUITING

Institut Curie, Paris

All Listed Sponsors
collaborator

Incyte Biosciences International Sàrl

INDUSTRY

lead

Institut Bergonié

OTHER