Polyprev: Study to Compare Fecal Immunochemical Test With Endoscopic Surveillance After Advanced Adenoma Resection in Fecal Immunochemical Test Colorectal Cancer Screening Programs.

NARecruitingINTERVENTIONAL
Enrollment

3,788

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2035

Conditions
Colorectal Cancer
Interventions
DIAGNOSTIC_TEST

Annual FIT

"Patients will be offered an annual FIT and colonoscopy will be performed if fecal hemoglobin concentration is ≥10µg / g of feces. After performing a colonoscopy the FIT will be sent to the patient:~* After one year if the unscheduled colonoscopy has been incomplete or a lesion requiring endoscopic surveillance has been completely resected.~* After five years if the colonoscopy has evaluated the entire mucosa, it is normal or with lesions that do not require endoscopic surveillance (1-2 non-advanced adenomas)."

PROCEDURE

Endoscopic surveillance.

First surveillance colonoscopy will be performed in three-year time. If an advanced adenoma or at least three non-advanced adenomas are detected, colonoscopy will be repeated after 3 years. In contrast, if colonoscopy is normal or 1-2 non-advanced adenomas are detected, colonoscopy will be repeated after 5 years.

Trial Locations (1)

32002

RECRUITING

Complexo Hospitalario Universitario de Ourense, Ourense

All Listed Sponsors
lead

Fundacin Biomedica Galicia Sur

OTHER

NCT04967183 - Polyprev: Study to Compare Fecal Immunochemical Test With Endoscopic Surveillance After Advanced Adenoma Resection in Fecal Immunochemical Test Colorectal Cancer Screening Programs. | Biotech Hunter | Biotech Hunter