300
Participants
Start Date
May 25, 2022
Primary Completion Date
July 15, 2026
Study Completion Date
July 15, 2026
Prolonged Exposure Therapy
A form of cognitive-behavioral psychotherapy focused on imaginal exposure to trauma memories and in vivo exposure to trauma reminders
Pharmacotherapy with paroxetine or venlafaxine XR
Standard dosing with paroxetine, a selectiveserotonin reuptake inhibitor that is FDA approved to treat PTSD and depression, or venlafaxine extended-release, a serotonin-norepinephrine reuptake inhibitor that is FDA approved to treat anxiety and depression
RECRUITING
Corporal Michael J. Crescenz VA Medical Center, Philadelphia
RECRUITING
Coatesville VA Medicial Center, Coatesville
RECRUITING
Birmingham VA Healthcare System, Birmingham
RECRUITING
Milwaukee VA Medical Center, Milwaukee
ACTIVE_NOT_RECRUITING
VA North Texas Healthcare System, Dallas
ACTIVE_NOT_RECRUITING
VA San Diego Healthcare System, San Diego
ACTIVE_NOT_RECRUITING
VA Palo Alto Healthcare System, Menlo Park
Patient-Centered Outcomes Research Institute
OTHER
Corporal Michael J. Crescenz VA Medical Center
FED
Coatesville VA Medical Center
UNKNOWN
Milwaukee VA Medical Center
FED
North Texas Veterans Healthcare System
FED
San Diego Veterans Healthcare System
FED
VA Palo Alto Health Care System
FED
Birmingham VA Health Care System
FED
University of Pennsylvania
OTHER