Fecal Filtrate as a Treatment Option of Multiple Recurrent Clostridioides Difficile Infection

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

238

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

December 1, 2024

Study Completion Date

December 1, 2025

Conditions
Clostridium Difficile InfectionRecurrent Clostridium Difficile Infection
Interventions
BIOLOGICAL

Fecal filtrate transplantation

"Patients will receive 5-8 encapsulated lyophilized fecal filtrate transplantations in enterosolvent, size 0 capsules. Before intervention patients will receive proton pump inhibitors and prokinetics. After the preparation, the participants will be instructed to swallow the capsules one by one within 5 minutes with fluid to help to swallow the capsules."

BIOLOGICAL

Conventional fecal microbiota transplantation

"Patients will receive 5-8 encapsulated lyophilized conventional fecal microbiota transplantations in enterosolvent, size 0 capsules. Before intervention patients will receive proton pump inhibitors and prokinetics. After the preparation, the participants will be instructed to swallow the capsules one by one within 5 minutes with fluid to help to swallow the capsules."

Trial Locations (1)

7624

Institute for Translational Medicine, University of Pécs, Pécs

All Listed Sponsors
lead

University of Pecs

OTHER

NCT04960306 - Fecal Filtrate as a Treatment Option of Multiple Recurrent Clostridioides Difficile Infection | Biotech Hunter | Biotech Hunter