NCT04957368View on ClinicalTrials.gov

Sustained Mood Improvement With Laughing Gas Exposure: A Randomized Controlled Pilot Trial

PHASE4CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

November 3, 2021

Primary Completion Date

February 27, 2024

Study Completion Date

February 27, 2024

Conditions
Treatment Resistant DepressionMajor Depressive Disorder
Interventions
DRUG

Nitrous Oxide 99 %

Nitrous oxide will be administered at an inspiratory concentration of 50% with concurrent intravenous saline (100ml) for one hour.

DRUG

Oxygen + Midazolam

Oxygen will be administered at 50% with intravenous midazolam (0.02mg/kg in 100ml) for one hour

Trial Locations (1)

M5B 1W8

St. Michael's Hospital, Toronto

All Listed Sponsors
lead

Unity Health Toronto

OTHER

NCT04957368 - Sustained Mood Improvement With Laughing Gas Exposure: A Randomized Controlled Pilot Trial | Biotech Hunter | Biotech Hunter