Comparing Efficacy and Safety Between Pertuzumab® and Perjeta® in Neoadjuvant Treatment of HER2+ Breast Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

214

Participants

Timeline

Start Date

August 11, 2018

Primary Completion Date

May 27, 2020

Study Completion Date

May 27, 2020

Conditions
HER2-positive Breast Cancer
Interventions
DRUG

Trastuzumab

An initial dose of 8 mg/kg, followed by 6 mg/kg every 3-weeks

DRUG

Pertuzumab

An initial dose of 840 mg, followed by 420 mg every 3-weeks

DRUG

Carboplatin

A dose of AUC6 (area under the plasma concentration-time curve) every 3-weeks

DRUG

Docetaxel

75 mg/m2 every 3-weeks

Trial Locations (44)

Unknown

Besat Clinic, Rasht

Dr. Behrouz Najafi's office, Rasht

Dr. Mehdi Mirblouk's office, Rasht

Razi Hospital, Rasht

Dr. Aboulqasem Allahyari's office, Mashhad

Imam Reza Hospital, Mashhad

Qaem Hospital, Mashhad

Sanabad Hospital, Mashhad

Arvand Hospital, Ahvāz

Baqaei Hospital, Ahvāz

Shafa Hospital, Ahvāz

Milad Hospital, Isfahan

Saba Clinic, Isfahan

Seyed-Al-Shohada Hospital, Isfahan

Sheikh Mofid Clinic, Isfahan

Dr. Behjat Kalantari's office, Kerman

Javad-Al-Aemeh Clinic, Kerman

Shahid Bahonar Hospital, Kerman

Dr. Mehrdad Payende's office, Kermanshah

Amir Hospital, Shiraz

Namazi Hospital, Shiraz

Shahid Faghihi Hospital, Shiraz

Shams Hospital, Tabriz

Baqiatallah Hospital, Tehran

BuoAli Hospital, Tehran

Dr. Safa Najjar Najafi's office, Tehran

Ebn-Sina Hospital, Tehran

Firoozgar Hospital, Tehran

Imam Khomeini Hospital, Tehran

Iran-Mehr Hospital, Tehran

Jam Hospital, Tehran

Jihad University Clinic, Tehran

Masih Daneshvari Hospital, Tehran

Massoud Clinic, Tehran

Mehrad Hospital, Tehran

Naft Hospital, Tehran

Rasool Akram Hospital, Tehran

Resalat Hospital, Tehran

Sajjad Hospital, Tehran

Sina Hospital, Tehran

Taleghani Hospital, Tehran

Tehran Hospital, Tehran

Toos Hospital, Tehran

Dr.Mortazavizadeh's office, Yazd

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Cinnagen

INDUSTRY