Effect of Dapagliflozin on Submaximal Exercise Tolerance in Heart Failure

PHASE2CompletedINTERVENTIONAL
Enrollment

3

Participants

Timeline

Start Date

October 22, 2021

Primary Completion Date

June 1, 2023

Study Completion Date

June 1, 2023

Conditions
HFrEF
Interventions
DRUG

Dapagliflozin 10Mg Tab

This will be a single-center randomized, placebo controlled, double-blind, 2-treatment, 2-phase cross-over trial in 27 HFrEF subjects: (A) Dapa 10 mg daily; (B) Placebo.

DRUG

Placebo

This will be a single-center randomized, placebo controlled, double-blind, 2-treatment, 2-phase cross-over trial in 27 HFrEF subjects: (A) Dapa 10 mg daily; (B) Placebo.

Trial Locations (1)

19054

University of Pennsylvania, Philadelphia

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Amgen

INDUSTRY

lead

University of Pennsylvania

OTHER