Baseline Oral Health Study: UnCoVer the Connections to General Health

PHASE4CompletedINTERVENTIONAL
Enrollment

186

Participants

Timeline

Start Date

September 28, 2021

Primary Completion Date

February 1, 2025

Study Completion Date

February 1, 2025

Conditions
Cardiovascular DiseasesDiabetes Type 2
Interventions
DRUG

Subgingival chlorhexidine irrigation

The dose information for the Chlorhexidine gluconate will be 0.12% with 1 mL in each dental pocket at a frequency of every 3 months for the duration of the study (18 months).

OTHER

Dental Supplies

Subjects in the Treatment Group will receive a commercial electric toothbrush (Colgate hum), toothpaste (Colgate Renewal), mouthwash (Colgate Zero), proxabrush (Colgate), and floss (Colgate Palmolive brand) to be used at home along with instructions on their use. Brush heads for the electric toothbrush will be replaced every 3 months and products (toothpaste, mouthwash, proxabrush, and floss) will be replenished at every site visit.

OTHER

Periodonal Treatment

Initial periodontal treatment consisting of a pre-procedural rinse and scaling \& root planing (SRP).

Trial Locations (2)

27599

University of North Carolina at Chapel Hill, Chapel Hill

28081

UNC Nutrition Research Institute, Kannapolis

All Listed Sponsors
collaborator

Colgate Palmolive

INDUSTRY

lead

University of North Carolina, Chapel Hill

OTHER

NCT04954313 - Baseline Oral Health Study: UnCoVer the Connections to General Health | Biotech Hunter | Biotech Hunter