Evolocumab or Normal Strategies to Reach LDL Objectives in Acute Myocardial Infarction Upbound to PCI

PHASE4RecruitingINTERVENTIONAL
Enrollment

2,166

Participants

Timeline

Start Date

September 29, 2021

Primary Completion Date

September 29, 2025

Study Completion Date

September 29, 2027

Conditions
STEMI - ST Elevation Myocardial InfarctionNSTEMI - Non-ST Segment Elevation MI
Interventions
DRUG

Evolocumab 140 MG/ML

Evolocumab (Repatha®) 140 mg every two weeks: first subcutaneous injection at the time of randomization, before PCI, followings during 12 months.

DRUG

Standard of care (SOC)

management as recommended in ESC/EAS 2019 guidelines, within reimbursement criteria

Trial Locations (1)

75013

RECRUITING

ACTION Group, Institut de Cardiologie, Centre Hospitalier Universitaire Pitié Salpêtrière (APHP), UPMC, Paris

Sponsors
All Listed Sponsors
collaborator

Action Research Group

OTHER

collaborator

Amgen

INDUSTRY

lead

Assistance Publique - Hôpitaux de Paris

OTHER