A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

1,000

Participants

Timeline

Start Date

July 9, 2021

Primary Completion Date

March 31, 2026

Study Completion Date

April 30, 2026

Conditions
Non-Alcoholic Fatty Liver Disease
Interventions
DRUG

Resmetirom

Tablet

Trial Locations (71)

10029

Mount Sinai Health System, New York

13057

Clarity Clinical Research, East Syracuse

23226

Bon Secours Liver Institute of Richmond, Richmond

23294

National Clinical Research - Richmond, Richmond

23298

Virginia Commonwealth University School of Medicine, Richmond

27710

Duke University Medical Center, Durham

28304

Cumberland Research Associates, Fayetteville

28557

Diabetes and Endocrinology Consultants, Morehead City

30060

Gastrointestinal Specialists of Georgia, Marietta

32127

Progressive Medical Research, Port Orange

32162

The Villages Research Center, The Villages

32216

Jacksonville Center for Clinical Research, Jacksonville

32806

Orlando Research Center, Orlando

33009

Velocity Clinical Research, Hallandale Beach (MD Clinical), Hallandale

33016

Floridian Clinical Research, Hialeah

33434

Excel Medical Clinical Trials, Boca Raton

33912

Covenant Research, Fort Myers

34211

Florida Research Institute, Lakewood Rch

34240

Covenant Research, Sarasota

34452

Nature Coast Clinical Research - Inverness, Inverness

35205

Central Research Associates, Birmingham

37040

Premier Medical Group - Clarksville - Dunlop Lane, Clarksville

38138

Gastro One - Germantown Office - Wolf Park Drive, Germantown

39216

Southern Therapy and Advanced Research, Jackson

39232

Gastrointestinal Associates & Endoscopy Center - Flowood, Flowood

40213

L-MARC Research Center, Louisville

43213

Aventiv Research Columbus, Columbus

43302

Awasty Research Network, Marion

50265

Iowa Diabetes Research, West Des Moines

60602

Chicago Research Center, Chicago

60611

Northwestern Memorial Physicians Group, Chicago

64131

Kansas City Research Institute, Kansas City

66606

Kansas Medical Clinic - Gastroenterology, Topeka

70072

Tandem Clinical Research - New Orleans Area Site, Marrero

70809

Digestive Health Center of Louisiana, Baton Rouge

71291

Clinical Trials of America, West Monroe

72117

Arkansas Gastroenterology, North Little Rock

75093

Plano Research Center, Plano

75203

The Liver Institute At Methodist Dallas, Dallas

75234

Dallas Research Center, Dallas

Liver Center of Texas, Dallas

76104

Texas Digestive Disease Consultants, Fort Worth

76710

Impact Research Institute, Waco

77030

Liver Associates of Texas, Houston

77598

Texas Digestive Disease Consultants - Bay Area Houston Endoscopy Center, Webster

78215

Texas Liver Institute/American Research Corporation, San Antonio

78229

Pinnacle Clinical Research - San Antonio, San Antonio

San Antonio Research Center, San Antonio

78504

Doctor's Hospital at Renaissance, McAllen

78539

South Texas Research Institute, Edinburg

78666

Texas Digestive Disease Consultants - San Marcos, San Marcos

78746

Pinnacle Clinical Research - Austin, Austin

80113

South Denver Gastroenterology - Swedish Medical Center Office, Englewood

84041

Wasatch Peak Family Practice, Layton

84123

Salt Lake City Research Center, Murray

85224

Arizona Liver Health - Chandler, Chandler

East Valley Family Physicians, Chandler

85306

The Institute For Liver Health - Glendale, Glendale

85711

The Institute For Liver Health - Tucson, Tucson

85712

Adobe Gastroenterology, Tucson

89052

Henderson Research Center, Henderson

90036

Ruane Clinical Research Group, Los Angeles

90048

Cedars-Sinai Medical Center, Los Angeles

90057

National Research Institute - Los Angeles, Los Angeles

90255

National Research Institute - Huntington Park, Huntington Park

91307

San Fernando Valley Health Institute, West Hills

91402

National Research Institute - Panorama City, Panorama City

93720

Fresno Clinical Research Center, Fresno

96814

East-West Medical Research Institute, Honolulu

98105

Liver Institute Northwest, Seattle

Unknown

Fundacion de Investigacion de Diego, San Juan

Sponsors
All Listed Sponsors
lead

Madrigal Pharmaceuticals, Inc.

INDUSTRY

NCT04951219 - A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE) | Biotech Hunter | Biotech Hunter