Fractionated CO2 Laser With and Without Clobetasol for Treatment of Vulvar Lichen Sclerosus

PHASE4CompletedINTERVENTIONAL
Enrollment

212

Participants

Timeline

Start Date

March 1, 2022

Primary Completion Date

April 25, 2025

Study Completion Date

April 25, 2025

Conditions
Vulvar Lichen Sclerosus
Interventions
DEVICE

Fractionated CO2-laser

All women will be undergoing FxCO2-laser therapy as this treatment is a criterion for enrollment.

DRUG

Clobetasol Propionate 0.05% Ointment

Clobetasol propionate 0.05% ointment obtained from a commercial manufacturer

Trial Locations (10)

10032

Columbia University, New York

18103

The Institute for Female Pelvic Medicine & Reconstructive Surgery, Allentown

20036

MedStar Health, Washington D.C.

20814

Walter Reed National Military Medical Center, Bethesda

43210

Ohio State University, Columbus

53188

Waukesha Memorial Hospital, Waukesha

60637

University of Chicago, Chicago

87106

The University of New Mexico, Albuquerque

92110

Kaiser Permanente - Southern California Permanente Medical Group, San Diego

02114

Massachusetts General Hospital, Boston

All Listed Sponsors
collaborator

Patty Brisben Foundation For Women's Sexual Health

OTHER

collaborator

Society of Gynecologic Surgeons

UNKNOWN

lead

Medstar Health Research Institute

OTHER