440
Participants
Start Date
August 12, 2021
Primary Completion Date
September 6, 2025
Study Completion Date
September 6, 2025
PFO closure device
Device PFO closure.
Aspirin and clopidogrel
Aspirin 100mg qd for 6 months and clopidogrel 75mg qd administered for 1month after device implanted.
Triptans
If migraine recurred, Triptans would be administered during the acute phase.
China-Japan Friendship Hospital of Jilin University, Changchun
Nanjing First Hospital, Nanjing
Tianjin Chest Hospital, Tianjin
Xiamen Cardiovascular Hospital Xiamen University, Xiamen
Xiangya Hospital Central South University, Changsha
Wuhan Asia Heart Hospital, Wuhan
Zhongnan hospital of wuhan university, Wuhan
Enshi Huiyi Hospital of Rheumatic Diseases, Enshi
Shangqiu First People's Hospital, Shangqiu
Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou
Guangdong Sanjiu Brain Hospital, Guangzhou
The Eighth Affiliated Hospital, Sun Yat-sen University, Guangzhou
Huizhou First People's Hospital, Huizhou
Shenzhen People's Hospital, Shenzhen
The Eighth Affiliated Hospital, Sun Yat-sen University, Guangzhou
Affiliated Hospital of Guangdong Medical University, Zhanjiang
Jiangmen Central Hospital, Jiangmen
The First People's Hospital of Nanning, Nanning
The people's hospital of Leshan, Leshan
Shanxi Cardiovascular Hospital, Taiyuan
Guangdong Provincial People's Hospital
OTHER