A Study to Explore the Effect of Acid-reducing Agents

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

July 7, 2021

Primary Completion Date

August 12, 2021

Study Completion Date

July 12, 2022

Conditions

Healthy Adults

Interventions

DRUG

Sitravatinib

100 mg sitravatinib on Day 1

DRUG

Pantoprazole

40 mg QD on Day 1 to Day 7 of Period 2 in Group 1

DRUG

Famotidine

40 mg PO 2 hrs after sitravatinib in Period 2 of Group 2

Trial Locations (1)

Covance Clinical Research Unit Inc., Madison