Savolitinib for Treating Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Patients

PHASE3CompletedINTERVENTIONAL
Enrollment

203

Participants

Timeline

Start Date

August 19, 2021

Primary Completion Date

November 30, 2024

Study Completion Date

November 30, 2024

Conditions
Non-small Cell Lung Cancer Metastatic
Interventions
DRUG

Savolitinib

Patients meeting the study inclusion criteria will receive Savolitinib \[Savolitinib 600 mg, po, once per day (QD) continuously in patients with baseline weight ≥50 kg, and Savolitinib 400 mg, po, QD in patients with baseline weight \<50 kg\] in 21 day treatment cycle, until disease progression, death, intolerable toxicity or other termination criteria as specified in the protocol, whichever occurs earliest. Or patient will receive Savolitinib \[Savolitinib 300 mg, po, twice per day (BID) continuously in patients with baseline weight ≥50 kg, and Savolitinib 200 mg, po, BID in patients with baseline weight \<50 kg\] in 21 day treatment cycle, until disease progression, death, intolerable toxicity or other termination criteria as specified in the protocol, whichever occurs earliest.

Trial Locations (1)

210000

Shanghai Chest Hospital, Shanghai

All Listed Sponsors
lead

Hutchison Medipharma Limited

INDUSTRY

NCT04923945 - Savolitinib for Treating Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Patients | Biotech Hunter | Biotech Hunter