Pharmacokinetics, Safety and Efficacy of Nemolizumab in Participants With Moderate-to-Severe Atopic Dermatitis

PHASE2CompletedINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

June 24, 2021

Primary Completion Date

April 28, 2025

Study Completion Date

April 28, 2025

Conditions
Moderate-to-Severe Atopic Dermatitis
Interventions
DRUG

Nemolizumab

Participants will receive subcutaneous (SC) injection of 10, 20 or 30 milligrams (mg) nemolizumab, every 4 weeks (Q4W) for 52 weeks with a loading dose of 20, 40 or 60 mg at Day 1 based on the body weight.

DRUG

Nemolizumab

Participants will receive SC injection of 5, 10 or 15 mg nemolizumab, Q4W for 52 weeks with a loading dose of 10, 20 or 30 mg at Day 1 based on the body weight.

Trial Locations (23)

1036

Galderma Investigational Site #6147, Budapest

2900

Galderma Investigational Site #6218, Hellerup

6720

Galderma Investigational Site #5531, Szeged

48322

Galderma Investigational Site #8560, West Bloomfield

92708-3701

Galderma Investigational Site #8636, Fountain Valley

92123-2746

Galderma Investigational Site #9937, San Diego

92083-6031

Galderma Investigational Site #9930, Vista

Galderma Investigational Site #9929, Coral Gables

46250-2041

Galderma Investigational Site #8142, Indianapolis

40217-1444

Galderma Investigational Site #8092, Louisville

48084-5260

Galderma Investigational Site #8155, Troy

11203-2012

Galderma Investigational Site #8242, Brooklyn

10032-3729

Galderma Investigational Site #9938, New York

73069-6301

Galderma Investigational Site #8206, Norman

19103-4708

Galderma Investigational Site #8255, Philadelphia

77706-3061

Galderma Investigational Site #9931, Beaumont

78218-3128

Galderma Investigational Site #78218-3128, San Antonio

90-265

Galderma Investigational Site #5570, Lodz

27-400

Galderma Investigational Site #6237, Ostrowiec Świętokrzyski

35-055

Galderma Investigational Site #5495, Rzeszów

02-953

Galderma Investigational Site #6262, Warsaw

51-685

Galderma Investigational Site #6261, Wroclaw

0850

Galderma Investigational Site #5896, Esplugues de Llobregat

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Galderma R&D

INDUSTRY