The Clinical Features and Pregnancy Outcomes of CTD Patients

RecruitingOBSERVATIONAL
Enrollment

126

Participants

Timeline

Start Date

September 11, 2018

Primary Completion Date

June 30, 2025

Study Completion Date

December 31, 2026

Conditions
Connective Tissue DiseasesPregnancy Related
Interventions
DRUG

Prednisone

5-30mg, po, once per day(Qd) prescribed if needed and adjusted due to patient response

DRUG

Hydroxychloroquine

100-200mg, po, twice per day (Bid) prescribed if needed and adjusted due to patient response.

DRUG

Aspirin

100mg, po, once per day (Qd) prescribed if needed and adjusted due to patient response to 32 weeks of pregnancy. 75mg po, once per day (Qd) to 34 weeks of pregnancy. 50mg po, once per day (Qd) to 36 weeks of pregnancy.

DRUG

low molecular weight heparin Enoxaparin

40-60mg, ih, Subcutaneous injection, once per day (Qd) or twice per day (Bid) if needed and adjusted due to patient response.

Trial Locations (1)

250012

RECRUITING

Qilu Hospital, Jinan

All Listed Sponsors
lead

Qilu Hospital of Shandong University

OTHER