150
Participants
Start Date
January 21, 2021
Primary Completion Date
February 2, 2027
Study Completion Date
February 2, 2027
Biospecimen Collection
Undergo collection of blood, saliva, stool, and bronchoalveolar lavage samples
Bronchoscopy with Bronchoalveolar Lavage
Undergo bronchoscopy with BAL
Chemoradiotherapy
Undergo concurrent chemoradiation per standard of care
Computed Tomography
Undergo computed tomography scan
Diagnostic Laboratory Biomarker Analysis
Correlative studies
Immune Checkpoint Inhibitor
Receive CPI per standard of care
Nasal Wash and Collection
Undergo nasal wash
Quality-of-Life Assessment
Ancillary studies
Questionnaire Administration
Ancillary studies
Spirometry
Under lung spirometry tests
RECRUITING
M D Anderson Cancer Center, Houston
M.D. Anderson Cancer Center
OTHER