Randomized, Double-Blind, Active Placebo-Controlled Study of Ketamine to Treat Levodopa-Induced Dyskinesia

PHASE2SuspendedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 5, 2021

Primary Completion Date

December 30, 2023

Study Completion Date

March 30, 2024

Conditions
DyskinesiasMovement DisordersCentral Nervous System DiseasesNervous System DiseasesNeurologic Manifestations
Interventions
DRUG

Ketamine

Ketamine is an FDA-approved N-methyl-D-aspartate (NMDA) receptor-modulating drug pharmacologically classified as an NMDA receptor antagonist (also noted to be a weak opioid receptor agonist).

DRUG

Midazolam

Midazolam is a benzodiazepine used for anesthesia, procedural sedation, trouble sleeping, and severe agitation.

Trial Locations (7)

33032

Investigative Site #3, Miami

33175

Investigative Site #6, Miami

48170

Investigative Site #4, Plymouth

60008

Investigative Site #5, Rolling Meadows

85719

Investigative Site #7, Tucson

91910

Investigative Site #2, Chula Vista

92708

Investigative Site #1, Fountain Valley

Sponsors

Lead Sponsor

All Listed Sponsors
lead

PharmaTher Inc.

INDUSTRY

NCT04912115 - Randomized, Double-Blind, Active Placebo-Controlled Study of Ketamine to Treat Levodopa-Induced Dyskinesia | Biotech Hunter | Biotech Hunter