Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis Subjects

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

131

Participants

Timeline

Start Date

August 24, 2021

Primary Completion Date

May 7, 2024

Study Completion Date

June 4, 2024

Conditions
Neurotrophic Keratitis
Interventions
BIOLOGICAL

CSB-001 Ophthalmic Solution 0.1%

CSB-001: human recombinant dHGF (5-amino acid deleted hepatocyte growth factor)

BIOLOGICAL

Vehicle Control

Matching vehicle control without the drug substance

Trial Locations (48)

11702

SightMD, Babylon

12159

Cornea Consultants of Albany, Slingerlands

15213

UPMC Eye Center, Pittsburgh

18202

Hazleton Eye Specialists, Hazle Township

19104

Scheie Eye Institute, Philadelphia

21287

Johns Hopkins Hospital, Baltimore

23502

Virginia Eye Consultants, Norfolk

27710

Duke Eye Center, Durham

29456

Carolina Cataract & Laser Center, Ladson

30339

Eye Consultants of Atlanta, Atlanta

32174

International Eye Associates, PA, Ormond Beach

32256

Bowden Eye and Associates, Jacksonville

33418

Bascom Palmer Eye Institute at Palm Beach Gardens, Palm Beach

33437

Advanced Research, Boynton Beach

33603

International Research Center, Tampa

38119

BLINK Research Center, LLC, Memphis

40517

Kentucky Eye Institute, Lexington

41017

Cincinnati Eye Institute, Edgewood

43212

The Ohio State University, Department of Ophthalmology and Visual Sciences, Columbus

46260

Price Vision Group, Indianapolis

46290

Midwest Cornea Associates, LLC, Carmel

55305

Minnesota Eye Consultants, Minnetonka

55436

Cornea and Contact Lens Institute of Minnesota, Edina

57108

Vance Thompson Vision, Sioux Falls

58104

Eye Consultants of North Dakota, Fargo

63131

Ophthalmology Associates, St Louis

64111

Tauber Eye Center, Kansas City

78212

Stuart A. Terry, MD PA, San Antonio

78712

University of Texas at Austin; The Mitchel and Shannon Wong Eye Institute, Austin

80045

University of Colorado - Dept. of Ophthalmology, Aurora

80120

Corneal Consultants of Colorado, Littleton

80907

Vision Institute, Colorado Springs

85331

Eye Care North, Cave Creek

90013

Nvision Clinical Research, LLC, Los Angeles

90041

Global Research Foundation, Los Angeles

90095

UCLA Stein Eye Institute, Los Angeles

90505

Atlantis Eyecare, Torrance

91107

California Eye Specialists Medical Group Inc., Pasadena

92122

Gordon Schanzlin New Vision Institute, San Diego

92354

Loma Linda University Eye Institute, Loma Linda

92562

LoBue Laser and Eye Medical Center, Inc., Murrieta

95670

Martel Eye Medical Group, Rancho Cordova

97210

Devers Eye Institute, Portland

02111

Tufts Medical Center, Boston

07650

Metropolitan Eye Research and Surgery Institute, Palisades Park

V5Z 1K1

Dr. Gregory Moloney, Vancouver

K1G 5L1

Precision Cornea Centre, Ottawa

M5T 3A9

Kensington Eye Institute, Toronto

Sponsors
All Listed Sponsors
lead

Claris Biotherapeutics, Inc.

INDUSTRY