The Gender Specific Effect on the Results of Ascending Aortic Replacement

CompletedOBSERVATIONAL
Enrollment

200

Participants

Timeline

Start Date

January 1, 2013

Primary Completion Date

June 1, 2022

Study Completion Date

July 1, 2023

Conditions
Ascending Aortic Aneurysm
Interventions
PROCEDURE

Ascending aortic replacement

Surgical access will be performed through a median sternotomy. Ascending aortic repair is performed under conditions of cardiopulmonary bypass (CPB) and MHCA with unilateral ACP via innominate artery with a flow rate of 8-10 ml/kg/min and perfusion pressure of 60-80 mmHg. Once CPB is instituted, the aortic cross-clamp is applied, and the heart is arrested with antegrade cardioplegia. Hemiarch replacement involves resection lesser curve of the aortic arch from the base of the innominate artery (Zone 0) to a point immediately distal to the nadir of the lesser curvature (Zone 3 or Zone 2 if the left subclavian artery was too far).

Trial Locations (1)

634012

Tomsk NRMC, Tomsk

All Listed Sponsors
lead

Tomsk National Research Medical Center of the Russian Academy of Sciences

OTHER

NCT04905225 - The Gender Specific Effect on the Results of Ascending Aortic Replacement | Biotech Hunter | Biotech Hunter