Statin TReatment for COVID-19 to Optimise NeuroloGical recovERy

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

190

Participants

Timeline

Start Date

March 10, 2022

Primary Completion Date

June 30, 2025

Study Completion Date

July 30, 2025

Conditions
Neurocognitive Impairment, Mild
Interventions
DRUG

Atorvastatin

40mg atorvastatin + standard care daily for 12 months.Atorvastatin 40mg has TGA approval for general marketing for the treatment of hypercholesterolaemia and cardiovascular prevention under a number of manufacturer names.The study medication selected will be the atorvastatin 40mg (Apotex) which is scored, and allows down-titration to 20mg should a participant develop symptoms.The study medication will be packaged, labelled and dispensed directly to particpants by the Syntro Health pharmacy in Australia. A comparable atorvastatin 40mg is being sourced in Chile, and will be dispensed from the pharmacy of the Clínica Alemana de Santiago. Similarly, a comparable atorvastatin 40mg is being sourced in Hong Kong, and will be dispensed from the site's pharmacy.

OTHER

Standard Care

Standard care for neurological symptoms as a result of COVID-19 infection.

Trial Locations (1)

2050

The George Institute for Global Health, Sydney

All Listed Sponsors
collaborator

University of Sydney

OTHER

collaborator

Monash University

OTHER

collaborator

The Alfred

OTHER

collaborator

Universidad del Desarrollo

OTHER

collaborator

Chinese University of Hong Kong

OTHER

collaborator

Clinica Alemana de Santiago

OTHER

lead

The George Institute

OTHER