Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease

PHASE2RecruitingINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

April 30, 2027

Study Completion Date

October 31, 2027

Conditions
Alzheimer Disease
Interventions
DRUG

Sargramostim

Sargramostim is a granulocyte macrophage colony stimulating factor that will be administered at a dose of 250 mcg/m2 per day subcutaneously, 5 days/week, for 24 weeks

DRUG

Saline - placebo comparator

Saline will be administered subcutaneously, 5 days/week, for 24 weeks

Trial Locations (1)

80045

RECRUITING

University of Colorado Anschutz Medical Campus, Aurora

Sponsors
All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

collaborator

Alzheimer's Association

OTHER

collaborator

Partner Therapeutics, Inc.

INDUSTRY

lead

University of Colorado, Denver

OTHER