50
Participants
Start Date
June 21, 2021
Primary Completion Date
May 31, 2025
Study Completion Date
May 31, 2025
M-CENK, Suspension for Infusion, Cryopreserved (M-CENK) (Cohort 2 part B)
M-CENK will be administered up to 10 times weekly via intravenous (IV) infusion starting on study day 1 with a minimum of 7 days between each M-CENK dose. The dose of MCENK will be 0.25 - 0.75 × 10e9 cells per infusion.
N-803 (Cohort 2 part B)
N-803 15 μg/kg will be administered subcutaneously prior to every other dose of M-CENK for up to 5 doses of N-803.
Apheresis collection of MNCs (part A)
Subjects in cohort 1A will participate in apheresis collection of lymphocytes (part A) and will not receive any investigational therapy in this study.
Chan Soon-Shiong Institute for Medicine, El Segundo
Hoag Memorial Hospital Presbyterian, Newport Beach
Lead Sponsor
ImmunityBio, Inc.
INDUSTRY