Randomized Trial of Curcumin to Reduce Mucositis in Autologous Transplant Setting

PHASE3RecruitingINTERVENTIONAL
Enrollment

190

Participants

Timeline

Start Date

December 16, 2018

Primary Completion Date

May 16, 2025

Study Completion Date

May 16, 2025

Conditions
Oral Mucositis (Ulcerative)
Interventions
DRUG

Curcumin Lozenges

Curcumin lozenges (each containing 100 mg of curcumin) will be given at a dose of 4 lozenges (total dose 400 mg curcumin) BD. Formulation is Solid Lipid Curcumin Particle (SLCP). Oral curcumin lozenges will be given from two days prior to receiving high dose chemotherapy till day+28 of transplant.

OTHER

Placebo Lozenges

Placebo lozenges will be given from two days prior to receiving high dose chemotherapy till day+28 of transplant.

Trial Locations (1)

410210

RECRUITING

Tata Memorial Centre, Navi Mumbai

All Listed Sponsors
lead

Tata Memorial Centre

OTHER