SeMaglutide and Albuminuria Reduction Trial in Obese Individuals Without Diabetes

PHASE3CompletedINTERVENTIONAL
Enrollment

125

Participants

Timeline

Start Date

March 14, 2022

Primary Completion Date

May 28, 2024

Study Completion Date

May 28, 2024

Conditions
ObesityAlbuminuria
Interventions
DRUG

Semaglutide

Patients will be treated for 24 weeks with semaglutide 3.0 mlg/ml s.c. once weekly. The starting dose of semaglutide will be 0.24 mg per week subcutaneous injection with increasing doses at 4, 8, 12, and 16 weeks to 0.5, 1,0, 1.7 and 2.4 mg.

DRUG

Placebo

Patients will receive a matching placebo sc. once weekly during the treatment period of 24 weeks.

Trial Locations (13)

3230

University of Calgary, Calgary

27880

Hospital Da Costa Burela, Lugo

46010

Hospital Clínico Universitario, Valencia

91054

University Hospital Erlangen, Erlangen

97080

University Hospital Wuerzburg, Würzburg

M5G 2C4

Division of Nephrology University Health Network, University of Toronto, Toronto

6815 AD

Rijnstate, Arnhem

8025 AB

Isala, Zwolle

9713 GZ

University Medical Center Groningen, Groningen

9728 NT

Martini Ziekenhuis, Groningen

7609 PP

Dept Internal Medicine, division of Nephrology Hospital Group Twente, Almelo

08035

Vall d'Hebron University Hospital, Barcelona

08907

Hospital Universitari de Bellvitge, Barcelona

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novo Nordisk A/S

INDUSTRY

lead

University Medical Center Groningen

OTHER

NCT04889183 - SeMaglutide and Albuminuria Reduction Trial in Obese Individuals Without Diabetes | Biotech Hunter | Biotech Hunter