Efficacy of Tocilizumab in Association to Steroids in Giant Cell Arteritis With Cerebro-vascular Involvement

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

September 24, 2021

Primary Completion Date

January 29, 2025

Study Completion Date

August 13, 2025

Conditions
Giant Cell ArteritisNeurovascular Disorder
Interventions
DRUG

Tocilizumab

"Tocilizumab will be administered subcutaneously at a dose of 162mg/0.9mL weekly (each week, on the same day) from week 0 to week 24.~At the first injection (Baseline D0), a therapeutic education is provided for patients/caregivers who can carry out the injections themselves as part of their usual care."

DRUG

Placebo

Placebo administered subcutaneously (SC) weekly during 24 weeks

Trial Locations (1)

75012

Saint Antoine Hospital, Neurology Unit, Assistance Publique-Hôpitaux de Paris, Paris

All Listed Sponsors
collaborator

Roche Chugai

INDUSTRY

collaborator

Roche Pharma AG

INDUSTRY

lead

Assistance Publique - Hôpitaux de Paris

OTHER