NCT04882605View on ClinicalTrials.gov

KIR Sequencing and Typing for Allograft in Nancy

CompletedOBSERVATIONAL
Enrollment

156

Participants

Timeline

Start Date

March 23, 2015

Primary Completion Date

July 25, 2019

Study Completion Date

July 25, 2019

Conditions
Stem Cell Transplant Complications
Interventions
GENETIC

MHC typing

Allelic genotyping resolution of MHC genes (HLA-A, -B, -C, -DRB1, -DQA1, -DQB1, -DPA1, -DPB1 and -DRB3/4/5) using Illumina technology.

GENETIC

KIR typing

Allelic genotyping resolution of all 13 KIR genes (KIR2DL1, KIR2DL2/2DL3, KIR2DL4, KIR2DL5A, KIR2DL5B, KIR2DS1, KIR2DS2, KIR2DS3, KIR2DS3/2DS5, KIR2DS4, KIR3DL1/3DS1, KIR3DL2, KIR3DL3), 2 KIR pseudogenes (KIR2DP1 and -3DP1) using Illumina technology.

GENETIC

Assessment of KIR-based prediction scores

Compiling donor/recipient MHC and KIR typings into 28 major KIR-based prediction scores

All Listed Sponsors
collaborator

University of Cambridge

OTHER

lead

Central Hospital, Nancy, France

OTHER

NCT04882605 - KIR Sequencing and Typing for Allograft in Nancy | Biotech Hunter | Biotech Hunter