Treatment for Speech and Language in Primary Progressive Aphasia

NAActive, not recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

July 1, 2017

Primary Completion Date

June 30, 2024

Study Completion Date

June 30, 2024

Conditions
Primary Progressive AphasiaSemantic DementiaSemantic Memory DisorderLogopenic Progressive AphasiaNonfluent Aphasia, ProgressiveAphasiaAphasia, Progressive
Interventions
BEHAVIORAL

Lexical Retrieval Training (LRT)

In person or via teletherapy: Participants work on producing spoken and written names of personally relevant target items using a self-cueing hierarchy. Treatment focuses on the use of strategies that capitalize on spared cognitive-linguistic abilities to support word retrieval. The participant completes two (one hour each) sessions per week with a clinician plus daily home practice exercises.

BEHAVIORAL

Video-Implemented Script Training for Aphasia (VISTA)

In person or via teletherapy: Participants work on producing personally relevant scripts of 4-6 sentences in length. Length and complexity of scripts are individually tailored. The participant completes 30 minutes per day of home practice, during which they speak in unison with a video/audio model of a healthy speaker clearly articulating the scripts. Biweekly (one hour each) sessions with a clinician target clear and accurate script production, script memorization, and conversational usage of scripts.

Trial Locations (2)

78712

University of Texas, Austin

94158

University of California San Francisco, San Francisco

All Listed Sponsors
collaborator

National Institute on Deafness and Other Communication Disorders (NIDCD)

NIH

collaborator

University of California, San Francisco

OTHER

lead

University of Texas at Austin

OTHER

NCT04881617 - Treatment for Speech and Language in Primary Progressive Aphasia | Biotech Hunter | Biotech Hunter