Bintrafusp Alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

March 1, 2022

Primary Completion Date

January 31, 2027

Study Completion Date

July 31, 2027

Conditions
Advanced Soft-tissue SarcomaMetastatic Soft-tissue Sarcoma
Interventions
DRUG

Bintrafusp alfa

Bintrafusp alfa will be administered by intravenous infusion on day 1 every 3 weeks at a fixed dose of 2400 mg.

DRUG

Doxorubicin

Doxorubicin will be administered by intravenous infusion on day 1 every 3 weeks at a fixed dose of 75 mg/m² for a maximum of 6 cycles

Trial Locations (8)

13000

NOT_YET_RECRUITING

Institut Paoli Calmette, Marseille

21079

NOT_YET_RECRUITING

Centre Georges François Leclerc, Dijon

31000

WITHDRAWN

IUCT Oncopole, Toulouse

33000

RECRUITING

Institut Bergonie, Bordeaux

69000

RECRUITING

Centre Léon Bérard, Lyon

75000

NOT_YET_RECRUITING

Institut Curie, Paris

86000

RECRUITING

CHU Poitiers, Poitiers

94805

WITHDRAWN

Institut Gustave Roussy, Villejuif

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

INDUSTRY

lead

Institut Bergonié

OTHER